MR Dictionary

Non-parametric methods with bounds of causal effect

A non-parametric method that estimates upper and lower bounds for an MR causal effect. The bounds are not the same as confidence intervals and reflect the upper and lower limits of an estimated distribution of causal effects. 

For this method to provide a valid causal estimate of the exposure on the outcome, genetic variants must satisfy the MR assumptions, but this method does not require any of the additional MR assumptions. This method can only be used in the situation of binary (or categorical with few levels) exposure, instrumental variable (IV) and outcome. A method for implementing these in Stata has been developed. 

References

Other terms in 'One-sample MR methods':