MR Dictionary

A deoxyribonucleic acid (DNA) molecule that carries a portion of all genetic material. Two homologous chromosomes carry the same collection of gene, but each gene can be represented by a different allele on the two homologues (a heterozygous individual). A gamete (egg or sperm) will receive one of these homologues, but not both. Humans have 22 pairs of autosomal homologous chromosomes and 1 pair of sex chromosomes.

Used to identify the position of a genetic variant within MR studies.

Schematic representation of chromosomes, DNA and genetic variants in a diploid cell. From Hartwig et al., with permission.
Figure 1.1 - Schematic representation of chromosomes, DNA and genetic variants in a diploid cell. From Hartwig et al., with permission.

References

Other terms in 'Useful genetic terms ':